Channelopathies in Heart Disease

This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field.

The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications.

The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.

Aceasta carte ofera o prezentare de specialitate a mecanismelor de aritmie legate de canalul ionic si descrie progrese importante in intelegerea noastra a modului in care disfunctia canalului ionic cauzeaza boli cardiace. Ambele, descoperirile stiintifice si implicatiile clinice sunt prezentate si discutate de oamenii de stiinta care au contribuit considerabil la domeniu. Cartea este organizata in trei parti: partea I trateaza mecanismele moleculare si electrofiziologice ale functiei si disfunctionalitatea canalelor ionice, partea II se concentreaza pe genetica si descoperirile clinice, in timp ce partea a III-a descrie noi tehnici de cercetare, utilizarea celulelor stem si a modelelor animale si ofera o perspectiva asupra investigatiilor si aplicatiilor viitoare. Cartea este scrisa pentru oamenii de stiinta in biologie cardiovasculara si neurostiinte si va fi de interes general pentru medicii in cardiologie, electrofiziologie cardiaca si discipline conexe.