Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

This book provides a comprehensive, state-of-the art review of hematopoietic stem cell transplantation (HSCT) for sickle cell disease (SCD). The book reviews new data about risk prediction for severe SCD, outlines the unique challenges of HSCT for patients with SCD, profiles the supportive care guidelines for patients who are undergoing HSCT, highlights our current understanding of the best transfusion support for SCD patients prior to, during and after HSCT, and provides new perspectives about the ethics of HSCT for pediatric patients with SCD. Published in the last few years, several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients are also placed in context with respect to current management.

Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.

Aceasta carte ofera o revizuire cuprinzatoare, de ultima generatie, a transplantului de celule stem hematopoietice (HSCT) pentru boala de celule falciforme (SCD). Cartea trece in revista date noi despre predictia riscului pentru SCD severa, prezinta provocarile unice ale HSCT pentru pacientii cu SCD, prezinta orientarile de ingrijire de sustinere pentru pacientii care sunt supusi HSCT, subliniaza intelegerea noastra actuala despre cel mai bun suport transfuzional pentru pacientii cu SCD inainte de, in timpul si dupa HSCT si ofera noi perspective cu privire la etica HSCT pentru pacientii pediatrici cu SCD.