HLA and Disease Associations

Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man.

Desi identificarea antigenelor HLA a avut o importanta clinica primara in transplantul 2 si a avut un mare interes de baza in genetica si antropologie umana, un bonus destul de neasteptat a fost determinarea faptului ca antigenii HLA sunt asociati cu susceptibilitatea bolii intr-o masura mai mare decat orice alt marker genetic cunoscut la om.