Biomarkers for Alzheimer's Disease Drug Development

This volume aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer's disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer's disease, cutting-edge developments in neuropathology and their relevance for Alzheimer's disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.



Authoritative and cutting-edge, Biomarkers for Alzheimer's Disease Drug Development aims to ensure successful results in the further study of this vital field.

Acest volum isi propune sa construiasca o noua generatie de experti cu o intelegere mai larga a subiectelor cheie din domeniul bolii Alzheimer. Capitolele ghideaza cititorii prin abordari inovatoare pentru descoperirea biomarkerilor noi in lichidul cefalorahidian, inovatia in biomarkeri pe baza de sange, o imagine de ansamblu cuprinzatoare a abordarilor imagistice prin rezonanta magnetica si imagistica moleculara si valoarea lor pentru dezvoltarea medicamentelor pentru boala Alzheimer, dezvoltari de ultima generatie in neuropatologie si relevanta lor pentru studiile bolii Alzheimer, noile strategii genomice pentru dezvoltarea biomarkerilor si subiecte conexe, inclusiv testarea neuropsihologica si metodele analitice avansate. materiale si reactivi, pas cu pas, protocoale de laborator usor de reprodus si sfaturi despre depanarea si evitarea capcanelor cunoscute. Autoritar si de ultima generatie, Biomarkeri pentru boala Alzheimer Dezvoltarea medicamentelor isi propune sa asigure rezultate de succes in studiul ulterior al acestui domeniu vital.