Patho-Epigenetics of Infectious Disease

Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization.

La infectia cronica, echilibrul celular epigenetic poate fi perturbat si, pe termen lung, prin reprogramarea epigenetica a genomului celulei gazda, contribuie la conversia maligna a celulelor anterior sanatoase, in multe cazuri precedate de stabilirea unui camp epigenetic de cancerizare .