Year in Human and Medical Genetics

The genetic dissection of human primary immunodeficiency is expanding at full speed, in at least two directions. Some investigators pursue the dissection of well-known clinical phenotypes, for which the count of genetic etiologies seems to be endless, whereas others begin the search for inborn errors underlying new phenotypes, infectious and otherwise. The field of primary immunodeficiency is also expanding in other ways, with new therapeutic approaches, and with the care of patients in regions of the world where these diseases were unheard of less than a decade ago. Volume III includes overviews of PIDs in India and the Middle East as well as additional papers on new developments in primary immunodeficiencies (PIDs) and insights into PID pathophysiology.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http: //ordering.onlinelibrary.wiley.com/subs....

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Disectia genetica a imunodeficientei primare umane se extinde la viteza maxima, in cel putin doua directii. Unii cercetatori urmaresc disectia unor fenotipuri clinice bine cunoscute, pentru care numarul etiologiilor genetice pare a fi nesfarsit, in timp ce altii incep sa caute erori innascute care stau la baza unor noi fenotipuri, infectioase si altele.